A pilot plant study has been made of the liberation characteristics of a nickel ore under different milling conditions. A series of runs were made ranging from fully autogenous grinding to semi-autogenous grinding with a ball load of 8%. The mill products were sized and assayed then analysed by QEM4SEM. This enabled a full liberation analysis to be carried out to see whether the autogenous grinding leads to improved liberation by promoting selective breakage. Though it is frequently claimed that fully autogenous grinding yields superior liberation this could not be detected in the present study.