Addressing the persistent challenge of fine particle flotation has been the subject of extensive research, focusing on various methodologies across different commodities at laboratory scales. While some progress has been made with proposed solutions, many remain impractical for large scale commercial implementation due to technical complexities and economic constraints. One promising approach gaining momentum involves the use of nano-bubbles (NB) and pico-bubbles (PB), especially those generated through hydrodynamic cavitation techniques, to enhance fine particle flotation. Despite demonstrating improvements in fine particle flotation, previous studies have largely overlooked the influence of cavitation intensity on flotation performance, a factor crucial for managing operating costs. This study aimed to investigate the impact of hydrodynamic cavitation intensity on the froth flotation performance of Cu-Ni ore. Comparative analyses were performed at consistent time intervals rather than identical residence times through the cavitation device. The results revealed that below the cavitation threshold, the cavitation device functioned primarily as a static mixer. However, higher cavitation intensity significantly improved Cu-Ni recoveries at various recirculation time intervals. Both lower and intermediate intensity levels above the threshold achieved superior recoveries to the base case, albeit slightly below the highest intensity scenario.