Best practice mine sampling should provide a detailed quantification of all potential sources of error at each stage of sampling, sample preparation and assaying.Quality assurance (QA) should include testing for and quantifying potential sampling errors, and should be the basis for establishing ongoing sampling protocols, should set error limits and define quality control (QC) procedures. QA should be within the framework of Theory of Sampling (TOS) but may not involve the estimation of the sampling constant and the application of Gy's formula.Best practice QC should be carried out efficiently and in a timely and cost-effective manner with regular reporting against the guidelines established by QA.This paper provides an assessment of, and checklist for, current best practice sampling QA/QC with examples from operating gold mines including the QA/QC of underground (UG) reverse circulation (RC) grade control.CITATION:Carswell, J T, 2017. Best practice sampling QA/QC for gold and base metal mining - including how to assess the applicability of underground reverse circulation grade control sampling, in Proceedings Tenth International Mining Geology Conference 2017, pp 297-304 (The Australasian Institute of Mining and Metallurgy: Melbourne).