This paper, describing milling practice at Mount Isa Mines, is one of a series covering milling methods and costs that is being published by the Bureau of Mines, United States Department of the Interior.The Mount Isa concentrator began operations in May 1931, by treating a mixture of oxidized and sulphide ores. Since March, 1935, only sulphide ores have been milled; this change involved major alterations to the flow sheet. The maximum capacity on mixed oxide and sulphide ores was 2,650 tons per day; the present capacity is approximately 1,880 tons of sulphide ore per day. The installation of additional Grushing, grinding, and flotation equipment when completed early in 1939 will increase the maximum capacity of the concentrator to 2;240 tons of sulphide ore daily.All tonnages in this paper are expressed in tons of 2,000 pounds, gallon measurements in terms of Imperial gallons of 27741 cubic inches, and costs in dollars at the rate of $4 United States currency to the Australian pound.